Medicines and patient safety
Inappropriate medicine prescribing, errors during medicine administration and lack of inter-professional cooperation on medicines are the most frequent causes of patient injury. The research group "Medicines and patient safety" combines pharmacoepidemiological medicine information, therapeutic drug monitoring and patient focused research. We use quantitative and qualitative methods from the fields of pharmacy practice, clinical pharmacy, clinical pharmacology, biopharmaceutical and medical biochemistry to study how patient safety can protected with increasingly medicine use.
Optimal medicine use and monitoring
We conduct research on changes in prescribing patterns and use of drugs in vulnerable patients groups with chronic diseases such as diabetes, epilepsy and mental illness, or complications related to age (children, elderly, pregnancy). For example, older patients commonly have extensive polypharmacy, and pharmacodynamic and pharmacokinetic factors change with increasing age. For many medicine groups monitoring and/or information is vital for optimal treatment in terms of the balance between efficacy and tolerability.
Inter-disciplinary collaboration on prescribing and medicine use
We study how increased collaboration between health professionals can improve medicine prescribing and medicines reconciliation, for example in interdisciplinary medicine reviews. Systematic tools (STOP, START, NORGEP etc.) have become common to improve prescribing quality. We are researching the effect of interdisciplinary collaboration in hospitals, nursing homes and home care services.
Patients' understanding of medicines and disease
Polypharmacy and increased medicalization increases the risk of improper use of drugs and side effects. Why do patients use medicines "wrongly"? How do patients sense that their medicines work? Do they have side effects? Does patient self-monitoring of blood glucose and INR actually improve treatment? We use qualitative methods to study how patients’ and relatives’ arguing that they must be listened to, in order to increase safety, improve efficiency and potentially give fewer side effects.